ELI5: Explain Like I'm 5

Sequence assembly

Okay kiddo, let me tell you about sequence assembly. You know how we have instructions for building things like Legos or puzzles? Well, living things like animals and plants also have instructions for how to grow and work properly. These instructions are called DNA, and they are made up of letters just like the ones we use to write words.

Sometimes scientists want to read the instructions from the DNA of a living thing. But DNA instructions are really long, and they're broken up into lots of small pieces. So, scientists have to put the small pieces of DNA back together like a giant puzzle. This process of putting the DNA pieces together is called sequence assembly.

Just like with a puzzle, it's not always easy to know where each piece of DNA belongs. Scientists use computers to help them figure out the best way to fit the pieces together. They compare the pieces to each other, and they look for places where the patterns match up. Once they have all the pieces in the right order, they can read the instructions in the DNA and learn more about how living things work.

So, just like assembling a puzzle, sequence assembly is about putting lots of small pieces together to make one big picture. And in this case, the picture is the instructions for a living thing.
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