ELI5: Explain Like I'm 5

Extracellular matrix

The body is made up of tiny things called cells which are like little building blocks. Cells come in many different shapes and sizes and they all have a job to do. They work together to keep us healthy and strong.

The extracellular matrix, or ECM for short, is like a really important blanket that surrounds our cells. It's made up of lots of different tiny things, like protein fibers, that hold all our cells together in a big structure called the tissues. It's like the glue that keeps everything in place.

Think of the ECM like a cake. The cake is made up of lots of little ingredients like sugar, flour, eggs and butter, but when they are all mixed together and baked, they create a yummy and solid cake. The same goes for the ECM. All the tiny fibers and other things that make it up work together to create a strong structure that supports and protects our cells.

The ECM does more than just create a framework for our cells. It also acts as a highway for important molecules and cells to travel through, like nutrients, hormones, and immune cells. These things can move around and communicate with each other through the ECM to help keep our body in balance.

So, in short, the extracellular matrix is like a big, strong blanket that surrounds our cells, holding them together and supporting them, while also allowing important things to pass through and communicate with one another. It's pretty important stuff!
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