ELI5: Explain Like I'm 5

Holographic interference microscopy

Okay kiddo, have you ever seen a hologram before? It's like a 3D picture that looks real even though it isn't really there. Well, holographic interference microscopy is kind of like that.

First, we need to know what microscopy is. It's when we use something called a microscope to look at really tiny things that we can't see with our eyes.

Now, imagine we have a tiny object that we want to look at, like a cell. We shine a special kind of light on the cell, and some of that light gets reflected off it. We then use a special camera to capture the light that gets reflected.

Here's where it gets cool. We take two different pictures of the reflected light, but from slightly different angles. When we put those pictures together, they create a 3D image of the cell.

But wait, there's more! We can also use that 3D image to measure things about the cell, like its size and shape. This can help us learn more about how cells work and how we can treat diseases.

So basically, holographic interference microscopy is a way for us to see and study really tiny things, like cells, using special lights and cameras to create 3D images. Isn't that neat?
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