Okay, imagine you have two hands, a right hand and a left hand. They look the same, but they are actually different because the fingers are arranged in a certain way. Similarly, in the world of molecules, there are two versions of a molecule that might look the same but are arranged in different ways. We call these versions "mirror images" or "enantiomers".
Now, this is where homochirality comes in. Imagine you have a bunch of molecules that are all the same, just like a bunch of identical blocks. Now, if you were to split these molecules in half, you might get some that are the right-handed version and some that are the left-handed version. This is called "racemic" mixture or "racemate". But in nature, we usually see only one of the version - either all the right-handed or all the left-handed version. This is what we call homochirality.
This might sound like a small difference, but in some cases, it can have very big effects. For example, some drugs can have different effects depending on whether they are the right or left-handed version. Understanding homochirality can help us understand more about how molecules work and how we can design better drugs.