Isolated hypogonadotropic hypogonadism is when the body doesn't make enough hormones that help us grow and develop like we're supposed to. These hormones are called gonadotropins (go-nad-o-tro-pins).
These hormones help our sex organs (like testicles and ovaries) develop normally, and they tell our bodies to make more hormones like testosterone (in boys) and estrogen (in girls). But if someone has hypogonadotropic hypogonadism, their body doesn't make enough of these hormones, and so their sex organs don't grow or work like they should.
This can cause problems like delayed puberty (when a person's body doesn't start changing like it should), smaller testicles or ovaries, and problems with fertility (when someone can't have babies). But, it's treatable! Doctors can give hormone treatments that help the body make the hormones it needs, and this can help things like puberty happen like they're supposed to.