An orphan drug is like a special medicine made just for a few people who have a very rare disease. It's called an orphan drug because the disease is so rare, there aren't many people who have it, and so making the medicine is not profitable for the company that makes it.
Sometimes, these rare diseases can be really serious or even life-threatening, and there might not be any other treatment available. So, the government decides to help by giving special incentives to companies that make orphan drugs. These incentives are designed to encourage the companies to make these medicines even though there might not be many people using them.
This might include things like getting extra funding to help with research and development, faster approval from medical regulators, and even exclusivity rights which means the drug company can be the only one to make the drug for a certain period of time.
Overall, making an orphan drug can be a long and difficult process, but it can also be really important for people who have rare diseases and need help.