Patch clamping is a scientific technique used by scientists to measure the electrical activity in tiny cells. It is done by attaching a special tool called a 'patch clamp' to the cell. The patch clamp has a tiny glass tube connected to it. When a scientist uses a patch clamp to measure the electrical activity in a cell, they place the glass tube so that it is touching the cell. They then use a special current to make a 'patch' on the cell membrane. This patch is like a little window that allows the scientist to measure the electrical activity of the cell.