ELI5: Explain Like I'm 5

Goldman equation

Okay, imagine you're at a swimming pool that has a bunch of different types of water. There's plain water, salty water, and sugary water. And let's say you have a friend who's really good at math, and she can figure out how easy or hard it is for you to swim in each type of water.

This is kind of what the Goldman equation does, but for cells in our brain (and other parts of our body) instead of swimmers in a pool. Our brain cells have little electric currents that make them work and communicate with each other, but the currents are affected by the different ions (like sodium, potassium, and chloride) that are in our cells and in the fluids surrounding them.

The Goldman equation helps scientists figure out how all those different ions affect the electrical currents in our cells. It takes into account things like the concentration of each ion inside and outside the cell, the charge of each ion, and how easily each ion can move across the cell membrane.

So in a way, the Goldman equation is like a super smart lifeguard who can tell you how hard it will be to swim in the different types of water in the pool. But instead of water, it's helping us understand how our brain cells work!