Spin column-based nucleic acid purification

Spin column-based nucleic acid purification is like using a special straw to suck out all the yucky stuff from a drink. But instead of a straw, it's a tiny tube with a bed of special materials that capture the nucleic acids, like DNA and RNA, from a mixture.

First, a sample of the mixture is placed in a tube with a solution that helps the nucleic acids bind to the special materials in the tube.

Then, the tube is put into a centrifuge machine that spins it very fast. This force helps move the mixture through the special materials in the tube and separates the nucleic acids from the rest of the mixture.

The liquid part of the mixture, which doesn't contain the nucleic acids, is spun out and discarded.

Finally, a special solution is added to the tube to wash the nucleic acids, and then they are released from the special materials by adding another solution.

The nucleic acids are then collected in a separate tube and can be used for scientific experiments or diagnostic tests.