ELI5: Explain Like I'm 5

Confocal laser scanning microscopy

Confocal laser scanning microscopy is like taking a special picture of tiny things using a special camera. Imagine you have a big, beautiful garden with lots of flowers in it. If you wanted to take a picture of the garden, you would usually use a regular camera and everything would be fuzzy and blended together. But with confocal laser scanning microscopy, it's like you're able to take a picture of just one flower at a time.

Instead of a regular camera, you use a special microscope that sends tiny laser beams onto the thing you want to look at. Then, it takes a picture of just the little bit of light that comes back from that one spot. This way, you can see every tiny detail of that spot without all the other stuff getting in the way.

It's kind of like shining a flashlight in a dark room to only see one thing at a time. But instead of a flashlight, it's lasers and instead of a room, it's super tiny things like cells or even the tiniest bits of a germ.

This kind of microscope is helpful for scientists who want to study really small things like the inside of living cells. Confocal laser scanning microscopy helps them see these tiny things more clearly so they can learn more about them.