ELI5: Explain Like I'm 5

Histone-modifying enzymes

Histone-modifying enzymes are like tiny machines that do important jobs in our cells. They help keep our DNA organized and make sure it works the right way. The way they do this is by changing the shape of the little caps (called histones) that keep our DNA wrapped up like a spool of thread. They add special molecules, called chemicals, to the histones so that our DNA can be read and copied more easily, which helps our cells function more efficiently. Sometimes the enzymes add extra things to the histones so that our cells remember certain instructions. That way, our cells know what to do in the future!